Resumen

QoL was measured using the MOS-HIV and SF-36 questionnaires; NCF using the Brief Neurocognitive Test(BNCS); anxiety and depression using theHospital Anxiety and Depression Scale (HADS-A and HADS-D, respectively) in HIV+/HIV- pairs matched by age and education status. For sexual sphere an ad-hoc designed survey was used. We analysed 108 mature HIV+ and 113 HIV- women who were enrolled in 29 hospital-sites (April-September 2011).103 HIV+/HIV well matched pairs. Age for HIV+ vs. HIV- mature women (mean±SD) was 45.3±5.6 vs. 45.1±5.6 years (p=0.84); race/ethnicity distribution was Caucasian, 89.8% vs. 82.3%l black,1.9% vs. 1.8%; and Hispanic, 7.4% vs. 15.9% (p=0.19), respectively. The mean anthropometric measures were not significantly different in HIV+ vs. HIV- women. The marital status showed less HIV+ married/living with a partner, 41.8% vs. 68.1%; more HIV+ widows, 19.4% vs. 5.3%, (p=0.002); and more HIV+ women with no children, 29.1% vs. 16.1% (p=0.02). Regarding sexual sphere, there was a trend to longer mean duration since menopause first symptoms in HIV+ women, as well as a trend for more vs. HIV- women referring menopause diagnosis, and significantly less percentage of HIV+ women were sexually active, 63.9% vs. 85.8% (p<0.001) and also less had stable partner, 64.8% vs. 83.2% (p=0.003); more HIV+ had decrease in libido, 49.1% vs. 33.6% (p=0.01) and longer duration of symptoms, 41.3±47.6 vs. 22.2±18.2 months (p=0.01). Pairs HIV+/HIV- comparison showed a trend to worst QoL, significant for “Pain” mean scores, 71±28 vs. 77±21 (p=0.03) and “Mental health”, 65±22 vs. 75±18 (p=0.001); significantly greater mean scores for HADS-A, 7.50±4.15 vs. 5.75±3.97 (p=0.002) and HADS-D, 4.38±4.18 vs. 2.41±2.57 (p<0.001). More HIV+ women had a positive screening results for NCF damage, 49.5% vs. 30.1% (p=0.003). Mature HIV+ women differ in social habits and sexual sphere from matched HIV- pairs. There was a trend for lower QoL scores and significantly greater proportion with positive screening tests for anxiety, depression and neurocognitive damage were reported in HIV+ vs. matched pairs of HIV- women. A multidimensional management with special focus on mental health and mood stage of the HIV+ women might be critical to improve their wellbeing facing aging and living with HIV. (Extraído del documento)