Catálogo general VIH/sida
Factors associated to late presentation of HIV newly diagnosed adolescents in Spain
Resumen
Purpose: Adolescents represent a growing share of new HIV diagnoses. Late presenters (LP) is a universal challenge that also affects adolescents. Nevertheless, data are scarce. Method: Retrospective study of LP (< 350 CD4/ul or AIDS-defining events at diagnosis) in HIV newly diagnosed adolescents (12-< 20years-old) included in CoRIS and CoRISpe Spanish cohorts until end 2017. CoRIS enrols HIV-naïve patients from adult units and CoRISpe from pediatric units. Demographic, clinical data and way of transmission were analysed. Results: From 357 HIV newly diagnosed adolescents, 123 (34.5%) were late presenters with a median CD4 rate of 235/ul at diagnosis. LP were mainly male (69.9%) and median age was 18.7 years, similar to general cohort. The main way of infection in LP was sexual (64.2%; 35.8% men who have sex with men (MSM) and 28.4% by heterosexual contact), 21.1% were injection drug users, 7.3% vertical transmission, 3.3% hemoderivates receivers. LP was significantly more frequent for heterosexual transmission (41.7%) than for MSM (23%), p=0.0023. Regarding the origin, 30.4% of MSM born outside Spain were LP vs 18.4% of Spanish MSM (p=0.0757). Foreign women with heterosexual transmission was a vulnerable group with 50% of LP vs 18.4% in Spanish MSM (p=0.0006). Despite mainly behaviourally transmission and younger age, LP rate for middle adolescents (15-17.9 years-old) was as high as for late adolescence (18-19.9 years-old): 34.6% vs 32%; p= 0.684. LP among adolescents decreased over time but not in the last 15 years: 34.3% in 2003-2007 vs 28.8% in 2013-2017 (p=0.504). Conclusion: More than 1/3 of HIV newly diagnosed adolescents were late presenters, with no decline in last 15 years. Adolescents with heterosexual transmission, foreign MSM and heterosexual foreign women presented higher LP rates. Specific approaches are needed to tackle this situation.
Autoría:
CERVANTES HERNÁNDEZ, Eloísa; EPALZA IBARRONDO, Cristina; ROJO CONEJO, Pablo; JIMÉNEZ DE ORY, Santiago; BERENGUER, Juan; GUTIÉRREZ RODERO, Félix; BERNAL MORREL, Enrique; FORTUNY GUASCH, Clàudia; FRICK, Marie Antoinette; SÁINZ COSTA, Talía; TORRES FERNÁNDEZ, David; RAMOS AMADOR, José Tomás; NAVARRO GÓMEZ, María Luisa
Autoría institucional: Grupo de Trabajo CoRISpe (Cohorte Nacional de Pacientes Pediátricos con VIH) (España); CoRIS (Cohorte de la Red de Investigación en Sida) (España)
Autoría institucional: Grupo de Trabajo CoRISpe (Cohorte Nacional de Pacientes Pediátricos con VIH) (España); CoRIS (Cohorte de la Red de Investigación en Sida) (España)
Ficha bibliográfica
- Año de publicación:
- 2019
- Descripción física:
- [1] p.
- Formato:
- Folleto
- Tipo de documento:
- Coloquios y ponencias
- Notas:
- Póster presentado en la 17th European AIDS Conference, celebrada del 6 al 9 de noviembre de 2019 en Basilea (Suiza).
- Más información:
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